Anti-Calnexin (Endoplasmic Reticulum Marker) Monoclonal Antibody(Clone: CANX/1543)
Produktgrößen
20 µg
£397,00
36-3412-20UG
100 µg
£716,00
36-3412-100UG
Über dieses Produkt
- SKU:
- 36-3412
- Zusätzliche Namen:
- Calnexin; CANX; CNX; IP90; Major histocompatibility complex class I antigen-binding protein p88; P90
- translate.label.attr.clone:
- CANX/1543
- Klonalität:
- Monoclonal
- Weitere Details:
- It recognizes a protein of 90kDa; which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds; amino-linked glycosylation and folding. To help proteins fold properly; the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding; endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins; facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
- Host:
- Mouse
- Immunogen:
- Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
