Anti-PAX8 (Renal Cell Marker) Monoclonal Antibody(Clone: PAX8/1491)
Produktgrößen
20 µg
£397,00
36-3386-20UG
100 µg
£716,00
36-3386-100UG
Über dieses Produkt
- SKU:
- 36-3386
- Zusätzliche Namen:
- Paired box 8; Paired box gene 8; paired box homeotic gene 8; Paired box protein Pax-8; Paired domain gene 8; PAX8
- translate.label.attr.clone:
- PAX8/1491
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 62kDa; identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis; thyroid follicular carcinomas; and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas); non-ciliated mucosal cells of the fallopian tubes; and simple ovarian inclusion cysts; but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous; endometrioid; and clear cell carcinomas; but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma; nephroblastoma; and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
