Anti-Carbonic Anhydrase VIII Monoclonal Antibody(Clone: CPTC-CA8-2)
Produktgrößen
20 µg
£397,00
36-3384-20UG
100 µg
£716,00
36-3384-100UG
Über dieses Produkt
- SKU:
- 36-3384
- Zusätzliche Namen:
- CA-VIII; CALS; CARP; MGC120502; MGC99509
- translate.label.attr.clone:
- CPTC-CA8-2
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However; the gene product lacks carbonic anhydrase activity (i.e.; the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect sµggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology; such as ataxia; mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally; it is upregulated in various cancers.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CA8 protein
- Isotyp:
- Mouse IgG2a
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
