Anti-ZAP70 (Chronic Lymphocytic Leukemia Marker) Monoclonal Antibody(Clone: ZAP70/2035)
Produktgrößen
20 µg
£397,00
36-3381-20UG
100 µg
£716,00
36-3381-100UG
Über dieses Produkt
- SKU:
- 36-3381
- Zusätzliche Namen:
- Selective T cell defect; SRK; STD; Syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70;TZK; Zeta chain associated protein kinase 70kDa
- translate.label.attr.clone:
- ZAP70/2035
- Klonalität:
- Monoclonal
- Weitere Details:
- ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells.Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human ZAP70 protein (around aa 247-382) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
