Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: rWT1/857)
Produktgrößen
20 µg
£397,00
36-3376-20UG
100 µg
£716,00
36-3376-100UG
Über dieses Produkt
- SKU:
- 36-3376
- Zusätzliche Namen:
- WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
- translate.label.attr.clone:
- rWT1/857
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a 47-55kDa-tumor suppressor protein; identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids; frequently found in subsets of sporadic Wilm's tumors.WT1; a sporadic and familial pediatric kidney tumor; is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1; a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium; and its expression has been sµggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells; malignant mesothelioma; ovarian carcinoma; gonadoblastoma; nephroblastoma; and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human WT1 protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
