Anti-Ubiquitin (Autophagy Marker) Monoclonal Antibody(Clone: UBB/3143R)
Produktgrößen
20 µg
£397,00
36-3341-20UG
100 µg
£716,00
36-3341-100UG
Über dieses Produkt
- SKU:
- 36-3341
- Zusätzliche Namen:
- Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2
- translate.label.attr.clone:
- UBB/3143R
- Klonalität:
- Monoclonal
- Weitere Details:
- Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process; it is first activated by forming a thiol-ester complex with the activation component E1; which is then transferred to ubiquitin-carrier protein E2; followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB; p53; cdc25A; Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression; differentiation; cell stress response; and apoptosis. Moreover; ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease; Lewy bodies seen in Parkinson's disease; and Pick bodies found in Pick's disease etc.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
