Anti-TSH-Receptor; B-Chain (Thyroid Marker) Monoclonal Antibody(Clone: TSHRB/1405)
Produktgrößen
20 µg
£397,00
36-3319-20UG
100 µg
£716,00
36-3319-100UG
Über dieses Produkt
- SKU:
- 36-3319
- Zusätzliche Namen:
- CHNG1; hTSHRI; LGR3; Thyroid-stimulating hormone receptor; Thyrotropin receptor; Thyrotropin receptor I; TSHR
- translate.label.attr.clone:
- TSHRB/1405
- Klonalität:
- Monoclonal
- Weitere Details:
- Thyroid-stimulating hormone (TSH; also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism; which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR); which is cleaved into two subunits; A and B; and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave's disease; an autoimmune disorder; TSHR is activated by autoantibodies; which may be stimulated by the cleavage of the A and B subunits.
- Host:
- Mouse
- Immunogen:
- Recombinant human TSHR; B-Chain protein
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
