Anti-CD284 (Toll-Like Receptor 4) Monoclonal Antibody(Clone: TLR4/230)
Produktgrößen
20 µg
£397,00
36-3271-20UG
100 µg
£716,00
36-3271-100UG
Über dieses Produkt
- SKU:
- 36-3271
- Zusätzliche Namen:
- ARMD10; CD284; hToll; TLR4; TOLL; Toll Endotoxin Hyporesponsiveness; Toll-like receptor 4
- translate.label.attr.clone:
- TLR4/230
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human TLR4 protein
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg