Anti-Tal1 Monoclonal Antibody(Clone: BTL73)
Produktgrößen
20 µg
£397,00
36-3226-20UG
100 µg
£716,00
36-3226-100UG
Über dieses Produkt
- SKU:
- 36-3226
- Zusätzliche Namen:
- bHLHa17; Class A basic helix-loop-helix protein 17; OTTHUMP00000009563; OTTHUMP00000009564; SCL; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell acute lymphocytic leukemia 1 protein; T
- translate.label.attr.clone:
- BTL73
- Klonalität:
- Monoclonal
- Weitere Details:
- Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia; making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition; leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length TAL1 protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg