Anti-STAT3 / Signal Transducer and Activator of Transcription 3 Monoclonal Antibody(Clone: STAT3/2409)
Produktgrößen
20 µg
£397,00
36-3218-20UG
100 µg
£716,00
36-3218-100UG
Über dieses Produkt
- SKU:
- 36-3218
- Zusätzliche Namen:
- APRF; HIES; ADMIO; ADMIO1
- translate.label.attr.clone:
- STAT3/2409
- Klonalität:
- Monoclonal
- Weitere Details:
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array; containing more than 19;000; full-length human proteins. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated throµgh phosphorylation in response to various cytokines and growth factors including IFNs; EGF; IL5; IL6; HGF; LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli; and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length STAT3 protein
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:2.jpg
