Anti-SREBP1 Monoclonal Antibody(Clone: SREBP1/1578)
Produktgrößen
20 µg
£397,00
36-3212-20UG
100 µg
£716,00
36-3212-100UG
Über dieses Produkt
- SKU:
- 36-3212
- Zusätzliche Namen:
- ADD 1; bHLHd1; Class D basic helix-loop-helix protein 1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1c; SREBP-1; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding
- translate.label.attr.clone:
- SREBP1/1578
- Klonalität:
- Monoclonal
- Weitere Details:
- The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins; thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region; designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted; the element is activated; the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified; including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors; designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human SREBF1 protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg