Anti-CD162 (Selectin P Ligand) Monoclonal Antibody(Clone: PSGL1/1567)
Produktgrößen
20 µg
£397,00
36-3144-20UG
100 µg
£716,00
36-3144-100UG
Über dieses Produkt
- SKU:
- 36-3144
- Zusätzliche Namen:
- CD162; CLA; Cutaneous lymphocyte associated antigen; P-selectin glycoprotein ligand 1; PSGL1; Selectin P ligand; SELPLG
- translate.label.attr.clone:
- PSGL1/1567
- Klonalität:
- Monoclonal
- Weitere Details:
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-; E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such; this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans; for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
- Host:
- Mouse
- Immunogen:
- Recombinant human SELPLG (CD162) protein
- Isotyp:
- Mouse IgM; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php