Anti-Bcl-6 (Follicular Lymphoma Marker) Monoclonal Antibody(Clone: BCL6/1526)
Produktgrößen
20 µg
£397,00
36-3108-20UG
100 µg
£716,00
36-3108-100UG
Über dieses Produkt
- SKU:
- 36-3108
- Zusätzliche Namen:
- B-cell lymphoma 5 protein; B-Cell Lymphoma 6 Protein; BCL5; BCL6; BCL6A; cys his2 zinc finger transcription factor; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor
- translate.label.attr.clone:
- BCL6/1526
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 95kDa; which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL); where CD10; bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast; anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
- Host:
- Mouse
- Immunogen:
- Recombinant human bcl-6 protein fragment (aa256-389) (Exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
