Anti-Rb1 (Tumor Suppressor Protein) Monoclonal Antibody(Clone: 1F8)
Produktgrößen
20 µg
£397,00
36-3083-20UG
100 µg
£716,00
36-3083-100UG
Über dieses Produkt
- SKU:
- 36-3083
- Zusätzliche Namen:
- OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein
- translate.label.attr.clone:
- 1F8
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a 105kDa phosphoprotein; identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast; esophageal; squamous cell and cervical carcinoma.
- Host:
- Mouse
- Immunogen:
- Recombinant human Rb1 protein fragment of 283 amino acid residues.
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
