Anti-CD45RA (Leukocyte Marker) Monoclonal Antibody(Clone: K4B5)
Produktgrößen
20 µg
£397,00
36-3067-20UG
100 µg
£716,00
36-3067-100UG
Über dieses Produkt
- SKU:
- 36-3067
- Zusätzliche Namen:
- B220; CD45R; GP180; Leukocyte common antigen (LCA); Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC); Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein
- translate.label.attr.clone:
- K4B5
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 205kDa-220kDa; identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A; B and C; respectively. The differential splicing of the exons generates at least five isoforms; ABC; AB; BC; B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells; 50% of peripheral CD8+ T-cells; B-cells; and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary; predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
