Anti-ACTH (Adrenocorticotrophic Hormone) (C-Terminus) Monoclonal Antibody(Clone: CLIP/2859R)
Produktgrößen
20 µg
£397,00
36-2962-20UG
100 µg
£716,00
36-2962-100UG
Über dieses Produkt
- SKU:
- 36-2962
- Zusätzliche Namen:
- Adrenocorticotropin; alpha or beta or gamma Melanocyte Stimulating Hormone (MSH) or Melanotropin; beta-Endorphin; beta or gamma Lipotropin (LPH); CLIP; Met Enkephalin; POC; POMC
- translate.label.attr.clone:
- CLIP/2859R
- Klonalität:
- Monoclonal
- Weitere Details:
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to CLIP (aa25-39 of ACTH); does not react with Synacthen (aa1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes throµgh extensive; tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP; ACTH; alpha-MSH (Melanocyte Stimulating Hormone); beta-MSH; gamma-MSH; CLIP (corticotropin-like intermediary peptide); Lipotropin-beta; Lipotropin-gamma; beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells; B-cells; and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH. '
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to aa25-39 of human ACTH (NGAEDESAEAFPLEF)
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg