Anti-PAX2 (Renal Cell & Ovarian Carcinoma Marker) Monoclonal Antibody(Clone: PAX2/1104)
Produktgrößen
20 µg
£397,00
36-2896-20UG
100 µg
£716,00
36-2896-100UG
Über dieses Produkt
- SKU:
- 36-2896
- Zusätzliche Namen:
- Paired box gene 2; paired box homeotic gene 2; paired box protein 2; Paired box protein Pax-2; Paired box protein Pax2
- translate.label.attr.clone:
- PAX2/1104
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 42kDa; which is identified as PAX2. It is a member of the paired box family of transcription factors; which is required for development and proliferation of the kidney; brain; and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region; which encodes a DNA-binding domain; enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system; eye; ear; and urogenital tract; and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system; including kidney; ureteric epithelium; fallopian tube epithelium; ovary and uterus. In tumors; PAX2 has been detected in renal cell carcinomas; Wilms' tumors; nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 223-354) human PAX2 protein (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
