Anti-ROR2 Monoclonal Antibody(Clone: ROR2/1911)
Produktgrößen
20 µg
£397,00
36-2880-20UG
100 µg
£716,00
36-2880-100UG
Über dieses Produkt
- SKU:
- 36-2880
- Zusätzliche Namen:
- BR; CD49 antigen-like family member B; ROR2; Collagen receptor; DX5; Glycoprotein Ia deficiency included (GPIa); Human platelet alloantigen system 5 (HPA5 included); Integrin alpha II (ITGA2); Platelet alloantigen Br(a); included; Platelet glycoprotein Ia/IIa; Platelet membrane glycoprotein Ia; VLA2
- translate.label.attr.clone:
- ROR2/1911
- Klonalität:
- Monoclonal
- Weitere Details:
- ROR2 (receptor tyrosine kinase-like orphan receptor 2); also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2); is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain; distally located serine-threonine-rich domains; an extracellular immunoglobulin-like domain; a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt-1 and Wnt-3; regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder; brachydactyly type B1; or the autosomal recessive skeletal disorder; Robinow syndrome.
- Host:
- Mouse
- Immunogen:
- Human cultured keratinocytes
- Isotyp:
- Mouse IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
