Anti-c-Myb Oncoprotein Monoclonal Antibody(Clone: MYB286)
Produktgrößen
20 µg
£397,00
36-2830-20UG
100 µg
£716,00
36-2830-100UG
Über dieses Produkt
- SKU:
- 36-2830
- Zusätzliche Namen:
- c-myb_CDS; efg; ONCOGENE AMV; Oncogene MYB; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
- translate.label.attr.clone:
- MYB286
- Klonalität:
- Monoclonal
- Weitere Details:
- The highly leukemogenic avian retrovirus E26 contains two oncogenes; v-Myb and v-Ets; which are expressed together as a fusion protein. The cellular homolog of v-Myb; designated c-Myb; encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel; leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially; but not exclusively; in immature hemopoietic cells and its expression decreases as cells differentiate.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide; corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein; coupled to KLH
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg