Anti-MTF1 Monoclonal Antibody(Clone: MTF1/2649)
Produktgrößen
20 µg
£397,00
36-2807-20UG
100 µg
£716,00
36-2807-100UG
Über dieses Produkt
- SKU:
- 36-2807
- Zusätzliche Namen:
- Metal regulatory transcription factor 1; Metal response element binding transcription factor 1; Metal responsive transcription factor 1; MRE-binding transcription factor 1; MTF1; Transcription factor MTF1; Zinc regulatory factor (ZRF)
- translate.label.attr.clone:
- MTF1/2649
- Klonalität:
- Monoclonal
- Weitere Details:
- The metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation; MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1; La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore; MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MTF1 protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
