Anti-MMP9 (Matrix Metalloproteinase 9) Monoclonal Antibody(Clone: SPM425)
Produktgrößen
20 µg
£397,00
36-2797-20UG
100 µg
£716,00
36-2797-100UG
Über dieses Produkt
- SKU:
- 36-2797
- Zusätzliche Namen:
- 82kDa matrix metalloproteinase-9; 92kDa gelatinase; 92kDa type IV collagenase; CLG 4B; CLG4B; Collagenase Type 4 beta; Collagenase type IV 92KD; Gelatinase 92KD; Gelatinase B; Gelatinase beta; GelatinaseB; GELB; Macrophage gelatinase; MANDP2; Matrix metallopeptidase 9 (gelatinase B; 92kDa gelatinase
- translate.label.attr.clone:
- SPM425
- Klonalität:
- Monoclonal
- Weitere Details:
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components; including collagen; gelatin; fibronectin; laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester; lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase; fibroblast collagenase or collagenase-1); and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53; and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
- Host:
- Mouse
- Immunogen:
- Recombinant human MMP9 protein fragment (around aa 22-166) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg