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Antikörper

Anti-CD99 / MIC2 (Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: MIC2/1495R)

Produktgrößen
20 µg
£397,00
36-2768-20UG
100 µg
£716,00
36-2768-100UG
Über dieses Produkt
SKU:
36-2768
Zusätzliche Namen:
12E7; E2 antigen; MIC 2X; MIC 2Y; MIC2; Protein MIC2; Surface antigen MIC2; T-cell surface glycoprotein E2
translate.label.attr.clone:
MIC2/1495R
Klonalität:
Monoclonal
Weitere Details:
Recognizes a sialoglycoprotein of 27-32kDa; identified as CD99; or MIC2 gene product; or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins; which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Althoµgh its function is not fully understood; CD99 is implicated in various cellular processes including homotypic aggregation of T cells; upregulation of T cell receptor and MHS molecules; apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes; cortical thymocytes; and granulosa cells of the ovary. Most pancreatic islet cells; Sertoli cells of the testis; and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors.
Host:
Rabbit
Immunogen:
Recombinant human MIC2 protein
Isotyp:
Rabbit IgG
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg