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Antikörper

Anti-MCM7 (Proliferation Marker) Monoclonal Antibody(Clone: MCM7/1468)

Produktgrößen
20 µg
£397,00
36-2751-20UG
100 µg
£716,00
36-2751-100UG
Über dieses Produkt
SKU:
36-2751
Zusätzliche Namen:
CDC47; DNA replication licensing factor MCM7; MCM7 mini chromosome maintenance deficient 7; Mini chromosome Maintenance 7; Mini chromosome maintenance protein 7; P1.1-MCM3; P1CDC47; P85MCM; PNAS146
translate.label.attr.clone:
MCM7/1468
Klonalität:
Monoclonal
Weitere Details:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array; containing more than 19;000; full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2; 4 and 6 proteins possesses DNA helicase activity; and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase; CDK4; is found to associate with this protein; and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Host:
Mouse
Immunogen:
Recombinant human MCM7 protein fragment (aa195-319)
Isotyp:
Mouse IgG2b
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Fig. 2: SDS-PAGE Analysis Purified MCM7 Mouse Monoclonal Antibody (MCM7/1468). Confirmation of Integrity and Purity of Antibody.
Fig. 3: Western Blot Analysis of MCF-7; HEK-293; A549; SKBr3; HeP2 lysate using MCM7 Mouse Monoclonal Antibody (MCM7/1468).
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using MCM7 Mouse Monoclonal Antibody (MCM7/1468) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array.
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using MCM7 Mouse Monoclonal Antibody (MCM7/1468) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array.