Anti-MBD1 (Methyl-CpG Binding Domain Protein 1) Monoclonal Antibody(Clone: CPTC-MBD1-1)
Produktgrößen
20 µg
£397,00
36-2741-20UG
100 µg
£716,00
36-2741-100UG
Über dieses Produkt
- SKU:
- 36-2741
- Zusätzliche Namen:
- CXXC-type zinc finger protein 3; CXXC3; MBD1; MECP1 COMPLEX; Methyl-CpG-binding domain protein 1 (MBD1); Protein containing methyl-CpG-binding domain 1 (PCM1); Regulator of fibroblast growth factor 2 (FGF 2) transcription (RFT)
- translate.label.attr.clone:
- CPTC-MBD1-1
- Klonalität:
- Monoclonal
- Weitere Details:
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2; MBD1; MBD2; MBD3; and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins; with the exception of MBD3; is capable of binding specifically to methylated DNA. MECP2; MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors; and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore; MBD1 may serve as a potential therapeutic target for pancreatic cancer.
- Host:
- Mouse
- Immunogen:
- Recombinant human MBD1 protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg