Anti-Lymphocyte Specific Protein 1 (LSP1) / pp52 Monoclonal Antibody(Clone: LSP1/3025)
Produktgrößen
20 µg
£397,00
36-2709-20UG
100 µg
£716,00
36-2709-100UG
Über dieses Produkt
- SKU:
- 36-2709
- Zusätzliche Namen:
- WP34; pp52; lymphocyte specific protein 1; leukocyte specific protein 1
- translate.label.attr.clone:
- LSP1/3025
- Klonalität:
- Monoclonal
- Weitere Details:
- LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding; leukocyte-specific (including B and T lymphocytes; granulocytes and macrophages); phosphoprotein. However; mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes; stromal cells and fibroblasts); sµggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5; which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA; tandem pairs of Ets and SP1 motifs; and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions; including cell motility and chemotaxis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human LSP1 protein (around aa174-278) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
