Anti-CD171 / NCAM-L1 (L1 Cell Adhesion Molecule) Monoclonal Antibody(Clone: SPM275)
Produktgrößen
20 µg
£397,00
36-2697-20UG
100 µg
£716,00
36-2697-100UG
Über dieses Produkt
- SKU:
- 36-2697
- Zusätzliche Namen:
- CAML1; HSAS1; Hyd; L1 Cell Adhesion Molecule; L1-NCAM; MASA; MIC5; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; Neural cell adhesion molecule L1; NILE; S10; SPG1
- translate.label.attr.clone:
- SPM275
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a cell surface protein of 220-240kDa; identified as L1 cell adhesion molecule. The L1CAM gene; which is located in Xq28; is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation; aphasia; shuffling gait; and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1; neural cell adhesion molecule (L1CAM) also plays an important role in axon growth; fasciculation; and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- Host:
- Mouse
- Immunogen:
- Homogenous suspension of 16-week human fetal brain
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg