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Antikörper

Anti-Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody(Clone: KRT14/2375)

Produktgrößen
20 µg
£397,00
36-2673-20UG
100 µg
£716,00
36-2673-100UG
Über dieses Produkt
SKU:
36-2673
Zusätzliche Namen:
CK-14; Dowling Meara; ebs3; ebs4; Epidermolysis Bullosa Simplex; k14; Keratin 14; Keratin Type I Cytoskeletal 14; Koebner; krt14; NFJ
translate.label.attr.clone:
KRT14/2375
Klonalität:
Monoclonal
Weitere Details:
Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia; some glandular epithelia; myoepithelium; and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore; this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics; and in identifying metaplastic carcinomas of the breast.
Host:
Mouse
Immunogen:
Recombinant human KRT14 fragment (around aa351-472) (exact sequence is proprietary)
Isotyp:
Mouse IgG2a; kappa
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg