Anti-Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody(Clone: SPM623)
Produktgrößen
20 µg
£397,00
36-2664-20UG
100 µg
£716,00
36-2664-100UG
Über dieses Produkt
- SKU:
- 36-2664
- Zusätzliche Namen:
- BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
- translate.label.attr.clone:
- SPM623
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb recognizes a protein of 56.5kDa; identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis; expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer; appears in the first suprabasal layers and increases in concentration towards the granular layer. However; CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm; clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm; clinical stages II and III); CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes; being preferentially detected in more-differentiated parts.
- Host:
- Mouse
- Immunogen:
- Cytoskeletal preparation extracted from human ectocervical epithelium
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg