Anti-Cytokeratin 6 (KRT6) (Basal Cell Marker) Monoclonal Antibody(Clone: KRT6/1702)
Produktgrößen
20 µg
£397,00
36-2652-20UG
100 µg
£716,00
36-2652-100UG
Über dieses Produkt
- SKU:
- 36-2652
- Zusätzliche Namen:
- CK6A; CK6B; CK6C; CK6D; CK6E; Keratin Type II Cytoskeletal 6A; Keratin Type II Cytoskeletal 6B; Keratin Type II Cytoskeletal 6C; Keratin Type II Cytoskeletal 6D; Keratin Type II Cytoskeletal 6E; KRT6; KRT6A; KRT6B; KRT6C; KRT6D; KRT6E
- translate.label.attr.clone:
- KRT6/1702
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb recognizes a protein of 56kDa; identified as cytokeratin 6 (CK6). In humans; multiple isoforms of Cytokeratin 6 (6A-6F); encoded by several highly homologous genes; have distinct tissue expression patterns; and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13; and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes; which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles; suprabasal cells of a variety of internal stratified epithelia; in epidermis; in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes; which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
- Host:
- Mouse
- Immunogen:
- Recombinant human keratin 6 protein
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg