Anti-Catenin; gamma (Cardiomyocyte Marker) Monoclonal Antibody(Clone: 11E4)
Produktgrößen
20 µg
£397,00
36-2629-20UG
100 µg
£716,00
36-2629-100UG
Über dieses Produkt
- SKU:
- 36-2629
- Zusätzliche Namen:
- ARVD12; Catenin (cadherin-associated protein); gamma 80kDa; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; Junction Plakoglobin; PDGB; PKGB
- translate.label.attr.clone:
- 11 E 4
- Klonalität:
- Monoclonal
- Weitere Details:
- It recognizes a protein of 80-87kDa; identified as gamma-catenin. The catenins (; ; and ) are ubiquitously expressed; cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. T-catenin; also referred to as VR22; is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. T-catenin binds to E-catenin as well as to -catenin; and it functions to inhibit Wnt signaling. CTNNA3; the gene that encodes for -T-catenin; is located on chromosome 10; and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.
- Host:
- Mouse
- Immunogen:
- Recombinant full length human plakoglobin; fused to maltose binding protein
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
