Anti-CD61 / Integrin 3 / Platelet Glycoprotein IIIa (Platelet Marker) Monoclonal Antibody(Clone: ITGB3/2145)
Produktgrößen
20 µg
£397,00
36-2620-20UG
100 µg
£716,00
36-2620-100UG
Über dieses Produkt
- SKU:
- 36-2620
- Zusätzliche Namen:
- BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP
- translate.label.attr.clone:
- ITGB3/2145
- Klonalität:
- Monoclonal
- Weitere Details:
- Reacts with human integrin beta3 (GPIIIa; vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor; soluble fibrinogen; fibronectin; vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow; as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
- Host:
- Mouse
- Immunogen:
- Recombinant human ITGB3 protein fragment (aa 385-490) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
