Anti-CD11c (Dendritic Cell Marker) Monoclonal Antibody(Clone: ITGAX/1242)
Produktgrößen
20 µg
£397,00
36-2612-20UG
100 µg
£716,00
36-2612-100UG
Über dieses Produkt
- SKU:
- 36-2612
- Zusätzliche Namen:
- CD11 antigen-like family member C; Complement component 3 receptor 4 subunit; Integrin alpha-X; integrin; alpha X (antigen CD11C (p150); alpha polypeptide); Leu M5 alpha subunit; Leukocyte adhesion glycoprotein p150 95 alpha chain; Myeloid membrane antigen alpha subunit; p150/95
- translate.label.attr.clone:
- ITGAX/1242
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 145kDa; identified as CD11c. CD11c (ITGAX); a member of the leukointegrin family; shares the same beta subunit with other members of the leukocyte adhesion molecule family; which includes CD11a (LFA-1); CD11b (MAC-1) and CD11d (ITGAD); but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis; cell migration; and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes; tissue macrophages; NK cells; and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
- Host:
- Mouse
- Immunogen:
- Recombinant human ITGAX protein fragment (aa 637-827) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
