Anti-IL-4 / Interleukin 4 Monoclonal Antibody(Clone: IL4/1597)
Produktgrößen
20 µg
£397,00
36-2591-20UG
100 µg
£716,00
36-2591-100UG
Über dieses Produkt
- SKU:
- 36-2591
- Zusätzliche Namen:
- B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF1; Binetrakin; BSF1; IGG1 induction factor; Il4e12; Interleukin 4 variant 2; Interleukin 4; isoform 1Lymphocyte stimulatory factor 1; MGC79402; Pitrakinra
- translate.label.attr.clone:
- IL4/1597
- Klonalität:
- Monoclonal
- Weitere Details:
- Interleukin-4 (IL-4); also designated B cell stimulatory factor-1; is a glycosylated cytokine secreted by activated T lymphocytes; basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2; TNF; while Th2 cells secrete IL-4; IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells; but suppress the production of IgM; IgA; IgG1; IgG2 and IgG3. It has been determined that Stat6 is rapidly tyrosine phosphorylated following stimulation of IL-3 or IL-4; but is not detectably phosphorylated following stimulation with IL-2; IL-12 or erythropoietin.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human IL-4 protein
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg