Anti-IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) Monoclonal Antibody(Clone: IGHM/1623)
Produktgrößen
20 µg
£397,00
36-2556-20UG
100 µg
£716,00
36-2556-100UG
Über dieses Produkt
- SKU:
- 36-2556
- Zusätzliche Namen:
- AGM1; IGHM; Constant Region of Heavy Chain of IgM; Ig Mu Chain C Region
- translate.label.attr.clone:
- IGHM/1623
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 75kDa; identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA); gamma (IgG); epsilon (IgE); or delta (IgD); heavy chains; T-cells; monocytes; granulocytes; or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states; hereditary deficiencies; myeloma; Waldenstrom's macroglobulinemia; chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias; plasmacytomas; and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
- Host:
- Mouse
- Immunogen:
- Heavy chain of human IgM
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg