Anti-CD50 / ICAM3 Monoclonal Antibody(Clone: 101-1D2)
Produktgrößen
20 µg
£397,00
36-2518-20UG
100 µg
£716,00
36-2518-100UG
Über dieses Produkt
- SKU:
- 36-2518
- Zusätzliche Namen:
- ICAMR; Intercellular adhesion molecule 3 (ICAM3)
- translate.label.attr.clone:
- 101-1D2
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds; identified as CD50 or ICAM-3 (WS: IV V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC; cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg