Anti-Histone H1 (Pan Nuclear Marker) Monoclonal Antibody(Clone: AE-4)
Produktgrößen
20 µg
£397,00
36-2456-20UG
100 µg
£716,00
36-2456-100UG
Über dieses Produkt
- SKU:
- 36-2456
- Zusätzliche Namen:
- H1(0); H1.1; H1.2; H1.3; H1.4; H1.5; H10; H1A; H1F0; H1F1; H1F2; H1F3; H1F4; H1F5; H1FNT; H1FOO; H1FT; H1FV; H1FX; H1t; H1T2; H1X; HANP1; His1; HisC; HIST1; HIST1H1A; HIST1H1B; HIST1H1C; HIST1H1D; HIST1H1E; HIST1H1T; Oocyte-specific histone H1; Testicular H1 histone
- translate.label.attr.clone:
- AE-4
- Klonalität:
- Monoclonal
- Weitere Details:
- Please note that this antibody is a recombinant Rabbit version of original anti-histone H1 antibody (Clone AE-4). Because the variable heavy (VH) and variable light (VL) domains are the same; recombinant antibody has the same exact reactivity as the original AE-4 MAb. There are several advantages of producing a recombinant version of a monoclonal antibody. For example; a recombinant antibody is a pure preparation of active immunoglobulin with no contaminating non-functional intact Ig or free light/heavy chains. Secondly; antibody can always be produced; even if hybridoma line is lost. Moreover; it adds the flexibility of converting the antibody to any species; isotype or format. Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A; H2B; H3; and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers; forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1; derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. This antibody is extensively used as a pan-nuclear marker.
- Host:
- Rabbit
- Immunogen:
- Nuclei of human leukemia biopsy cells
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
