Anti-Histone H1 (Pan Nuclear Marker) Monoclonal Antibody(Clone: rAE-4)
Produktgrößen
20 µg
£397,00
36-2454-20UG
100 µg
£716,00
36-2454-100UG
Über dieses Produkt
- SKU:
- 36-2454
- Zusätzliche Namen:
- His1; HisC; HIST1; HIST1H1A; HIST1H1B; HIST1H1C; HIST1H1D; HIST1H1E; HIST1H1T; Oocyte-specific histone H1; Testicular H1 histone
- translate.label.attr.clone:
- rAE-4
- Klonalität:
- Monoclonal
- Weitere Details:
- Please note that this antibody is a recombinant Mouse version of original anti-histone H1 antibody (Clone AE-4). Because the variable heavy (VH) and variable light (VL) domains are the same; recombinant antibody has the same exact reactivity as the original AE-4 MAb. There are several advantages of producing a recombinant version of a monoclonal antibody. For example; a recombinant antibody is a purer preparation of active immunoglobulin with no contaminating non-functional intact Ig or free light/heavy chains. Secondly; antibody can always be produced; even if hybridoma line is lost. Moreover; it adds the flexibility of converting the antibody to any species; isotype or format.Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A; H2B; H3; and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers; forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1; derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. This antibody is extensively used as a pan-nuclear marker.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human Histone H1 protein
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
