Anti-MSH6 (DNA Mismatch Repair Protein) Monoclonal Antibody(Clone: MSH6/2927)
Produktgrößen
20 µg
£397,00
36-2439-20UG
100 µg
£716,00
36-2439-100UG
Über dieses Produkt
- SKU:
- 36-2439
- Zusätzliche Namen:
- DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; MSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein
- translate.label.attr.clone:
- MSH6/2927
- Klonalität:
- Monoclonal
- Weitere Details:
- The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially; inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family; GTBP (also designated MSH6); is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings sµggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
