Anti-CD13 / Aminopeptidase-N (Myeloid Cell Marker) Monoclonal Antibody(Clone: B-F10)
Produktgrößen
20 µg
£397,00
36-2418-20UG
100 µg
£716,00
36-2418-100UG
Über dieses Produkt
- SKU:
- 36-2418
- Zusätzliche Namen:
- Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; gp150; hAPN; Lap1; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p150; PEPN
- translate.label.attr.clone:
- B-F10
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes an integral membrane glycoprotein of 150kDa; identified as CD13 (also known as aminopeptidase-N). The CD13 antigen is present on most cells of myeloid origin including granulocytes; monocytes; mast cells; and GM-progenitor cells. It is also expressed by the majority of AML; CML in myeloid blast crisis; and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes; platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells; epithelial cells from renal proximal tubules and intestinal brush border; bone marrow stromal cells; osteoclasts; and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN); a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides; in phagocytosis; and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment sµggests that it may be important in myeloid cell differentiation.
- Host:
- Mouse
- Immunogen:
- KG-1 myeloid cells
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php