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Antikörper

Anti-Blood Group Antigen A (CD173) Monoclonal Antibody(Clone: HE-10)

Produktgrößen
20 µg
£397,00
36-2406-20UG
100 µg
£716,00
36-2406-100UG
Über dieses Produkt
SKU:
36-2406
Zusätzliche Namen:
A transferase; ABO; B transferase; CD173; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood
Anwendung:
Agglutination
translate.label.attr.clone:
HE-10
Klonalität:
Monoclonal
Weitere Details:
This MAb preferably reacts with determinants of chain A and H type 3(Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R); but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A; B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type; and are detected on erythrocytes; certain epithelial cells; and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens; including A; B; H; Lewis A; Lewis B; Lewis X; Lewis Y; and precursor type 1 chain antigens.
Host:
Mouse
Immunogen:
Mixture of erythrocytes of blood group Aand glyco protein fraction isolated from the saliva of secretors with blood group A
Isotyp:
Mouse IgM; kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg