Anti-PAI-RBP1 / SERBP1 / SERPINE1 Monoclonal Antibody(Clone: SERBP1/3495)
Produktgrößen
20 µg
£397,00
36-2366-20UG
100 µg
£716,00
36-2366-100UG
Über dieses Produkt
- SKU:
- 36-2366
- Zusätzliche Namen:
- CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI1 RNA-binding protein 1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1 mRNA binding protein 1
- translate.label.attr.clone:
- SERBP1/3495
- Klonalität:
- Monoclonal
- Weitere Details:
- PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein); also known as SERBP1 (SERPINE1 mRNA-binding protein 1); CGI-55; CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein); HABP4L or PAI-RBP1; is a membrane-associated protein that localizes to the nucleus; the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability; as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition; PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterone's antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer; sµggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
