Anti-Filaggrin (Keratinocyte Differentiation Marker) Monoclonal Antibody(Clone: FLG/1563)
Produktgrößen
20 µg
£397,00
36-2293-20UG
100 µg
£716,00
36-2293-100UG
Über dieses Produkt
- SKU:
- 36-2293
- Zusätzliche Namen:
- ATOD2; Epidermal Filaggrin; Filaggrin; Filaggrin precursor; Fillagrin; FLG; Profilaggrin
- translate.label.attr.clone:
- FLG/1563
- Klonalität:
- Monoclonal
- Weitere Details:
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor; profilaggrin (consisting of multiple filaggrin units of 324 aa each); which is localized in keratohyalin granules; and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer; sµggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
- Host:
- Mouse
- Immunogen:
- Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
