Anti-CD32 (Fc Gamma RIIa) Monoclonal Antibody(Clone: FCGR2A/479)
Produktgrößen
20 µg
£397,00
36-2280-20UG
100 µg
£716,00
36-2280-100UG
Über dieses Produkt
- SKU:
- 36-2280
- Zusätzliche Namen:
- CD32A; Fc fragment of IgG low affinity IIa receptor; Fc gamma RIIa; FCGR2A; FcgRII; IGFR2; IgG Fc receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-a; Ly-17; Ly-m20; LyM-1; Lymphocyte antigen 17
- translate.label.attr.clone:
- FCGR2A/479
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb binds most strongly to the IIa isoforms of CD32 (FcRII); a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis; cytotoxicity; and immunomodulation as well as platelet aggregation. Three genes (A; B; and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing; i.e.; IIa1; IIa2; IIb1; IIb2; IIb3 and IIc. Monocytes/macrophages; placental trophoblasts and endothelial cells express all isoforms. In addition; the IIb isoform is expressed by B cells; and the IIa isoform by platelets; granulocytes and; weakly; by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.
- Host:
- Mouse
- Immunogen:
- Recombinant human FCGR2A protein
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg