Anti-Protocadherin FAT2 (FAT Atypical Cadherin 2) Monoclonal Antibody(Clone: 8C5)
Produktgrößen
20 µg
£397,00
36-2277-20UG
100 µg
£716,00
36-2277-100UG
Über dieses Produkt
- SKU:
- 36-2277
- Zusätzliche Namen:
- FAT tumor suppressor homolog 2 (HFAT2); cadherin family member 8 (CDHF8); cadherin-related family member 9 (CDHR9); multiple EGF-like domains protein 1; multiple epidermal growth factor-like domains 1 (MEGF1); multiple epidermal growth factor-like domains protein 1; protocadherin FAT2.
- translate.label.attr.clone:
- 8C5
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 480kDa; which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus; which is characterized by a series of five homologous repeats; the most distal of which is thoµght to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins; including -catenin; to regulate cadherin function. The cadherin superfamily includes cadherins; protocadherins; desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain; two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule; controlling cell proliferation and playing an important role in cerebellum development.
- Host:
- Mouse
- Immunogen:
- Purified recombinant human FAT2 fusion protein.
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
