Anti-ETS1 (Marker of Tumor Metastasis) Monoclonal Antibody(Clone: ETS1/1801)
Produktgrößen
20 µg
£397,00
36-2259-20UG
100 µg
£716,00
36-2259-100UG
Über dieses Produkt
- SKU:
- 36-2259
- Zusätzliche Namen:
- Avian erythroblastosis virus E26 (v ets) oncogene homolog 1; ETS1; EWSR2; p54; v-ets erythroblastosis virus E26 oncogene homolog 1
- translate.label.attr.clone:
- ETS1/1801
- Klonalität:
- Monoclonal
- Weitere Details:
- ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases; cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells; where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting; activated and apoptotic lymphocytes.
- Host:
- Mouse
- Immunogen:
- Recombinant human ETS1 fragment (around aa137-230) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
