Anti-ER-beta-1 (Estrogen Receptor beta-1) Monoclonal Antibody(Clone: ESR2/3207)
Produktgrößen
20 µg
£397,00
36-2258-20UG
100 µg
£716,00
36-2258-100UG
Über dieses Produkt
- SKU:
- 36-2258
- Zusätzliche Namen:
- Erb; ESR BETA; ESR2; ESRB; ESTRB; estrogen nuclear receptor beta variant a; estrogen nuclear receptor beta variant b; estrogen receptor 2 (ER beta); estrogen receptor beta 4
- translate.label.attr.clone:
- ESR2/3207
- Klonalität:
- Monoclonal
- Weitere Details:
- Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors; including ER-alpha and ER-beta; contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus; thoµgh some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events; including dissociation from heat shock proteins; receptor dimerization; phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence sµggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even thoµgh they share many functional characteristics.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human ESR2 protein
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
