Anti-ER-beta-1 (Estrogen Receptor beta-1) Monoclonal Antibody(Clone: ERb455)-CF488
Produktgrößen
0.5 at 100 ml at µg/ml
£716,00
36-2256-0.5AT100MLATUG
Über dieses Produkt
- SKU:
- 36-2256
- Zusätzliche Namen:
- Erb; ESR BETA; ESR2; ESRB; ESTRB; estrogen nuclear receptor beta variant a; estrogen nuclear receptor beta variant b; estrogen receptor 2 (ER beta); estrogen receptor beta 4
- translate.label.attr.clone:
- ERb455
- Klonalität:
- Monoclonal
- Konjugat:
- CF488
- Weitere Details:
- Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors; including ER-alpha and ER-beta; contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus; thoµgh some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events; including dissociation from heat shock proteins; receptor dimerization; phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence sµggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even thoµgh they share many functional characteristics.
- Host:
- Mouse
- Immunogen:
- C-terminus fragment of recombinant human estrogen receptor beta protein
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg