Anti-ERCC1 / RAD10 (Tumor Progression Marker) Monoclonal Antibody(Clone: ERCC1/2318)
Produktgrößen
20 µg
£397,00
36-2239-20UG
100 µg
£716,00
36-2239-100UG
Über dieses Produkt
- SKU:
- 36-2239
- Zusätzliche Namen:
- COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
- translate.label.attr.clone:
- ERCC1/2318
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 110kDa; identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae; which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC); squamous cell carcinoma of the head; ovarian cancer and esophageal cancer.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
- Isotyp:
- Mouse IgG2b; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
