Anti-Desmoglein-1 (DSG1) Monoclonal Antibody(Clone: 32-2B)
Produktgrößen
20 µg
£397,00
36-2176-20UG
100 µg
£716,00
36-2176-100UG
Über dieses Produkt
- SKU:
- 36-2176
- Zusätzliche Namen:
- Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG1; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
- translate.label.attr.clone:
- 32-2B
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of ~150kDa; identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family.Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1; Dsg2; Dsg3; and Dsg4 isoforms.Within the desmosome; the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins; whereas the intracellular domain is essential for binding to the desmosomal plaque protein; plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
- Host:
- Mouse
- Immunogen:
- Bovine desmoglein (desmosomal glyco protein I) from nasal epidermis.
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
