Anti-CD55 / Decay Accelerating Factor (DAF) Monoclonal Antibody(Clone: 143-30)
Produktgrößen
20 µg
£397,00
36-2155-20UG
100 µg
£716,00
36-2155-100UG
Über dieses Produkt
- SKU:
- 36-2155
- Zusätzliche Namen:
- CD55; CD55 Cromer blood group system; Complement decay-accelerating factor; CROM; DAF; GPI-DAF; Decay Accelerating Factor for Complement; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form
- translate.label.attr.clone:
- 143-30
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a single chain glycoprotein of 70kDa; identified as CD55/DAF. It is widely expressed on cells throµghout the body including leukocytes; erythrocytes; epithelium; endothelium; and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases; C4b2a and C3bBb; and the C5-convertase; C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 may be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
- Host:
- Mouse
- Immunogen:
- PHA stimulated human PBL
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
